I often get asked by clients to provide details of what is, and more importantly what isn’t, supported in their environment.  This normally focuses on the versions of Office installed,  the browsers used and sometimes what happens if we block ActiveX controls.  This overview is quickly followed by a ‘Can we have a document on this’ request to which I generally send the following

Microsoft SharePoint Products and Technologies Document: Microsoft Office Programs and SharePoint Products and Technologies Integration – Fair, Good, Better, Best

This white paper describes how different versions of Office programs work together with the 2003 and 2007 versions of SharePoint technologies. Although an overview of the integration features of Microsoft Office 2000 versus Microsoft Office XP with Microsoft Windows SharePoint Services 3.0 and Microsoft Office SharePoint Server 2007 is provided, the paper’s focus is on the integration features of the Office 2003 Editions versions the 2007 Office Suites with the 2007 SharePoint Products and Technologies.

http://www.microsoft.com/downloads/details.aspx?FamilyId=E0D05A69-F67B-4D37-961E-2DB3C4065CB9&displaylang=en

Plan browser support (Office SharePoint Server)

Microsoft Office SharePoint Server 2007 supports several Web browsers that are commonly used. However, there are certain browsers that might cause some Office SharePoint Server 2007 functionality to be downgraded, limited, or available only through alternative steps. This article provides a detailed breakdown on what is supported in which browser and on what platform.

http://technet2.microsoft.com/Office/en-us/library/ff6c5b8c-59bd-4079-8f0b-de4f8b4e0a861033.mspx?mfr=true

I have not found any published information on 64bit browser support.

ActiveX controls and components used in Office SharePoint Server 2007

This article provides details about the ActiveX controls and components that are used in rendering features and content in these browsers. This information is useful for troubleshooting issues and for supporting end users in accomplishing tasks that they need to perform by using Office SharePoint Server 2007.

http://technet2.microsoft.com/Office/en-us/library/4fba0222-8b7a-4ae1-af64-e8050263784e1033.mspx?mfr=true

It is worth noting that this post is looking at SharePoint as a collaboration tool and helping to answer some common business questions.   It is not going to answer questions about accessibility, you need to read the update to my SharePoint Accessibility – Is MOSS 2007 accessible? ; and if you are looking at using SharePoint as publishing site it has been shown that SharePoint can be designed to meet your requirements although there is still conjecture over the misuse of the terms ‘accessible’ and ‘compatible’.